Mongolian gerbil as a model for immunological pharmacology.

The Mongolian gerbil as a model for lead toxicity. I. Studies of acute poisoning.

Mongolian gerbils fed diets containing lead acetate maintained body weight comparable to gerbils fed the same diet without added lead. Intranuclear lead inclusion bodies in epithelial cells of the proximal convoluted tubules of the kidney were first observed at 4 weeks, and increased in number to about 50 per high power field at 12 weeks. At this time, a corticomedullary area of empty-appearing...

The Mongolian Gerbil as a Model for the Analysis of Peripheral and Central Age-Dependent Hearing Loss

The Mongolian Gerbil as a Model for the Analysis of Peripheral and Central Age-Dependent Hearing Loss

Placental Development in the Mongolian Gerbil

Early gerbil development was studied from days 4 through 12 of gestation. Implantation occurs on day 8 in a shallow antimesometrial implantation crypt. The proamniotic cavity forms from an invagination of basal trophoblast and a folding together of the rim of the cup thus produced. The approximation of this rim gives rise to the ectoplacental cone. The further development and expansion of the e...

The Mongolian Gerbil as a Model for the Analysis of Peripheral and Central Age-Dependent Hearing Loss

Age-dependent hearing loss involves pathological changes affecting the peripheral as well as the central auditory system. The Mongolian Gerbil is a rodent with an average life span of 3-4 years, which shows, in contrast to mice and rats, sensitive hearing in the frequency range that is important for human communication. Consequently, gerbils have been used to study structural and functional asp...